Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 1.00 |
| ▸ | CA12 | O43570 | 10/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 6/20 | 1.00 |
| ▸ | CA1 | P00915 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | GLA | P06280 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | CASP1 | P29466 | 4/20 | 1.00 |
| ▸ | CASP7 | P55210 | 4/20 | 1.00 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Umbelliferone SCHEMBL22018 | 1.00 | CA9 (1.00) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL29396070 | 1.00 | CA9 (1.00) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL29624448 | 1.00 | CA9 (1.00) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL2767044 | 0.98 | CA9 (0.96) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL27700116 | 0.98 | CA9 (0.96) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL27427599 | 0.98 | CA9 (0.96) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL27915972 | 0.98 | CA9 (0.96) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL307982 | 0.98 | CA9 (0.96) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL29001874 | 0.96 | CA9 (0.92) | CA9CA12MCL1KDM4EALDH1A1 | |
| Umbelliferone SCHEMBL27896245 | 0.96 | CA9 (0.92) | CA9CA12MCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071588-B | Uridine phosphamide prodrug, preparation method and application thereof in medicine | 江苏天士力帝益药业有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-105056009-B | A kind of Chinese medicine composition for treating canine lumbar vertebral disease | 广西大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-109071588-A | Uridine phosphamide prodrug, preparation method and application thereof in medicine | 江苏天士力帝益药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107382934-A | A kind of mercapto-functionalized coumarin derivative and its preparation method and application | 福州大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-105315118-A | Integrated extracting and separating method for active ingredients of Chinese stellera roots | LI YUSHAN | 2016-02-10 | — | — | CN | disclosed |
| CN-105056009-A | Traditional Chinese medicine composition for treating canine lumbar vertebra disease | UNIV GUANGXI | 2015-11-18 | — | — | CN | disclosed |
| US-4374925-A | PROTEIN BINDING ASSAYS | SYVA COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| US-4275149-A | IMMUNOASSAY | SYVA COMPANY (US) | 1981-06-23 | — | — | US | disclosed |