Umbelliferone

Umbelliferone

SCHEMBL22018

O=c1ccc2ccc(O)cc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 11/20 1.00
CA12 O43570 10/20 1.00
MCL1 Q07820 7/20 1.00
KDM4E B2RXH2 7/20 1.00
ALDH1A1 P00352 6/20 1.00
AKR1B1 P15121 6/20 1.00
CA1 P00915 6/20 1.00
HPGD P15428 5/20 1.00
HSD17B10 Q99714 5/20 1.00
GLA P06280 5/20 1.00
GAA P10253 5/20 1.00
CASP1 P29466 4/20 1.00
CASP7 P55210 4/20 1.00
ERAP1 Q9NZ08 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 2/20 1.00
LMNA P02545 3/20 0.64
CYP1A2 P05177 3/20 0.64
PTGS1 P23219 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Umbelliferone SCHEMBL11137587 1.00 CA9 (1.00) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL29396070 1.00 CA9 (1.00) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL29624448 1.00 CA9 (1.00) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL2767044 0.98 CA9 (0.96) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL27700116 0.98 CA9 (0.96) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL27427599 0.98 CA9 (0.96) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL27915972 0.98 CA9 (0.96) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL307982 0.98 CA9 (0.96) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL29001874 0.96 CA9 (0.92) CA9CA12MCL1KDM4EALDH1A1
Umbelliferone SCHEMBL27896245 0.96 CA9 (0.92) CA9CA12MCL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 54852 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2026099761-A1 PEPTIDES SALEM YAHYA AHMED (EG) 2026-05-15 WO claimed
WO-2026102332-A1 NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF Blaze Bioscience, Inc. (US) 2026-05-15 WO claimed
EP-4724075-A2 SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF DOUBLE-STRANDED RNA Promega Corporation (US) 2026-04-15 EP claimed
EP-4720206-A1 INVISIBLE FLUORESCENT SOLVENT INK JET INK COMPOSITIONS Videojet Technologies, Inc. (US) 2026-04-08 EP claimed
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 US claimed
US-20260091047-A1 THERAPEUTIC COMBINATIONS FOR MOVEMENT DISORDERS NATIVE CODE BIO LLC (US) 2026-04-02 US claimed
US-20260062581-A1 INVISIBLE FLUORESCENT SOLVENT INK JET INK COMPOSITIONS VIDEOJET TECHNOLOGIES INC. (US) 2026-03-05 US claimed
EP-4168255-B1 ELASTOMERIC COMPOSITION COMPRISING A PHENOLIC COMPOUND AND A COMPOUND FROM THE MONOSACCHARIDE FAMILY MICHELIN & CIE (FR) 2026-03-04 EP claimed
US-4411946-A FORGERY-PROOF PAPER BAYER AKTIENGESELLSCHAFT (DE) 1983-10-25 US claimed
EP-0022768-B1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS SYVA COMPANY (US) 1983-10-05 EP claimed
US-4398031-A Coumarin derivatives and method for synthesizing 5'-methyl psoralens therefrom THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-08-09 US claimed
US-4334020-A Method of producing L-glutamic acid by fermentation AJINOMOTO COMPANY INCORPORATED (JP) 1982-06-08 US claimed
US-4296039-A REACTING 2-HALORESORCINOLS OR THEIR MONOETHERS WITH BETA-KETO ESTERS FIDIA S.P.A. (IT) 1981-10-20 US claimed
US-4275149-A IMMUNOASSAY SYVA COMPANY (US) 1981-06-23 US claimed
EP-0022768-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1981-01-28 EP claimed
EP-0022768-A4 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1980-08-18 EP claimed
WO-1979000882-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS SYVA CO (US) 1979-11-01 WO claimed
US-3950322-A DETECTION OF NEURAMINIDASE RESEARCH CORPORATION (US) 1976-04-13 US claimed