Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.67 |
| ▸ | RELA | Q04206 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | ACR | P10323 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133722 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL13749536 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL4955236 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL13783614 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9855583 | 0.99 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL21124189 | 0.99 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL4171854 | 0.99 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL21084423 | 0.99 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL21084486 | 0.99 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL16476681 | 0.99 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385844-A | THERMOSENSITIVE NON-CHLOLESTERIC COMPOUND AND ALKYLBENZOATE LIQUID CRYSTALS | BECTON, DICKINSON AND COMPANY (US) | 1983-05-31 | — | — | US | disclosed |
| US-4296631-A | AND METHOD OF MODIFYING THE HYSTERETIC BEHAVIOR | BECTON, DICKINSON AND COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4140016-A | CHOLESTERIC LIQUID CRYSTAL THERMOMETERS, BENZOIC ESTER DERIVATIVES | BECTON, DICKINSON AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-4128312-A | INDIUM AND/OR TIN OXIDES | HUGHES AIRCRAFT COMPANY (US) | 1978-12-05 | — | — | US | disclosed |