Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.62 |
| ▸ | PGR | P06401 | 9/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SHBG | P04278 | 3/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476181 | 0.91 | AR (0.62) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL6467277 | 0.91 | AR (0.62) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL6467275 | 0.91 | AR (0.62) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL9340441 | 0.89 | AR (0.59) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL5974247 | 0.87 | ESR1 (0.49) | ARPGRNR3C2LMNACYP3A4 | |
| Mibolerone SCHEMBL14275154 | 0.86 | AR (0.67) | ARPGRNR3C2LMNACYP3A4 | |
| Mibolerone SCHEMBL565277 | 0.86 | AR (0.67) | ARPGRNR3C2LMNACYP3A4 | |
| Mibolerone SCHEMBL4362587 | 0.86 | AR (0.67) | ARPGRNR3C2LMNACYP3A4 | |
| Mibolerone SCHEMBL10603681 | 0.86 | AR (0.67) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL24476600 | 0.84 | AR (0.64) | ARPGRNR3C2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4412993-A | 7-A-METHYLTESTOSTERONES | THE UPJOHN COMPANY (US) | 1983-11-01 | — | — | US | disclosed |