Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.67 |
| ▸ | PGR | P06401 | 8/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.67 |
| ▸ | SHBG | P04278 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mibolerone SCHEMBL565277 | 1.00 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL10603681 | 1.00 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL14275154 | 1.00 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL15201510 | 0.91 | AR (0.60) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL24476602 | 0.90 | SHBG (0.56) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL24476600 | 0.88 | AR (0.64) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL24476182 | 0.87 | AR (0.63) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL24476180 | 0.86 | AR (0.62) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL24476181 | 0.86 | AR (0.62) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL5700326 | 0.86 | AR (0.63) | ARPGRNR3C2SHBGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238310-A1 | MODULATION OF SEX STEROID HORMONE PRODUCTION AND ACTIVITY FOR TREATING AND PREVENTING HERNIAS | NORTHWESTERN UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| US-20210283144-A1 | MODULATION OF SEX STEROID HORMONE PRODUCTION AND ACTIVITY FOR TREATING AND PREVENTING HERNIAS | NORTHWESTERN UNIVERSITY | 2021-09-16 | — | — | US | disclosed |
| US-7582622-B2 | Steroids having a mixed androgenic and progestagenic profile | N.V. ORGANON (NL) | 2009-09-01 | — | — | US | disclosed |
| EP-1720895-B1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | ORGANON NV (NL) | 2007-09-19 | — | — | EP | disclosed |
| US-20070155836-A1 | Steroids having a mixed androgenic and progestagenic profile | AKZO NOBEL N.V. (NL) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155836-A1 | Steroids having a mixed androgenic and progestagenic profile | NR5A1, SHBG, HSD3B2 | AR 18/4885PGR 34/4885NR3C2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.