Methacrylic Acid

Methacrylic Acid

SCHEMBL11141850

C=C(C)C(=O)O.C=C(C)C(=O)O.OCc1ccccc1CO

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.44
CYP4A11 Q02928 2/20 0.44
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
HPGD P15428 3/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
APOBEC3G Q9HC16 1/20 0.40
BRD4 O60885 2/20 0.39
BRD9 Q9H8M2 1/20 0.39
BAZ2B Q9UIF8 1/20 0.39
BAZ2A Q9UIF9 1/20 0.39
AKR1B1 P15121 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
CTBP2 P56545 1/20 0.38
AKR1C3 P42330 1/20 0.38
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicyl Alcohol SCHEMBL9577921 0.88 AKR1B1 (0.52) PDCD1CD274HPGDLMNAGAA
Benzyl Alcohol SCHEMBL5039741 0.83 TSHR (0.61) LMNAALDH1A1KDM4EBAZ2BBAZ2A
Triphenylene SCHEMBL29117647 0.81 KDM4E (0.47) HPGDLMNAGAAALDH1A1KDM4E
Methacrylic Acid SCHEMBL29127403 0.81 AKR1B1 (0.48) AKR1B1
Methacrylic Acid SCHEMBL38660130 0.81 FOLH1 (0.41) HPGDL3MBTL1ALDH1A1KDM4EAKR1B1
Methacrylic Acid SCHEMBL331459 0.81 FOLH1 (0.41) HPGDL3MBTL1ALDH1A1KDM4EAKR1B1
Methacrylic Acid SCHEMBL25408174 0.80 TDP1 (0.42) HPGDLMNAGAAL3MBTL1ALDH1A1
Biphenyl SCHEMBL28832981 0.78 SMN1; SMN2 (0.48) HPGDLMNAGAAL3MBTL1ALDH1A1
SCHEMBL13243302 0.78 HPGD (0.46) CYP4F2CYP4A11PDCD1CD274HPGD
Methacrylic Acid SCHEMBL732426 0.78 HSPA5 (0.61) ALDH1A1KDM4EAKR1B1PKMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4414278-A NONAGGLOMERATING, NONSWELLING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-08 US disclosed