Methacrylic Acid

Methacrylic Acid

SCHEMBL331459

C=C(C)C(=O)O.C=C(C)C(=O)O.SCc1ccccc1CS

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.41
DCLRE1A Q6PJP8 1/20 0.41
DCLRE1B Q9H816 1/20 0.41
ALDH1A1 P00352 3/20 0.40
IDO1 P14902 2/20 0.40
KDM4E B2RXH2 1/20 0.40
AKR1B1 P15121 1/20 0.38
HPGD P15428 1/20 0.37
CTBP2 P56545 1/20 0.37
AKR1C3 P42330 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ELANE P08246 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL38660130 1.00 FOLH1 (0.41) FOLH1DCLRE1ADCLRE1BALDH1A1IDO1
Methacrylic Acid SCHEMBL11141850 0.81 CYP4F2 (0.44) ALDH1A1KDM4EAKR1B1HPGDCTBP2
Acrylic Acid SCHEMBL38659792 0.77 AKT1 (0.45) FOLH1DCLRE1ADCLRE1BALDH1A1IDO1
Methacrylic Acid SCHEMBL732426 0.76 HSPA5 (0.61) ALDH1A1IDO1KDM4EAKR1B1
Benzenethiol SCHEMBL28102582 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDAKR1C3ELANE
Benzenethiol SCHEMBL20545213 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDAKR1C3ELANE
Methacrylic Acid SCHEMBL28990064 0.75 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDAKR1C3L3MBTL1
Biphenyl SCHEMBL29002594 0.75 SMN1; SMN2 (0.56) ALDH1A1KDM4EHPGDAKR1C3L3MBTL1
Biphenyl SCHEMBL36673 0.75 SMN1; SMN2 (0.56) ALDH1A1KDM4EHPGDAKR1C3L3MBTL1
Naphthalene SCHEMBL3422961 0.75 KDM4E (0.47) ALDH1A1KDM4EHPGDAKR1C3ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-20220137261-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND CANON KABUSHIKI KAISHA (JP) 2022-05-05 US disclosed
CN-112118955-B Automatic injection method of mold for monomer for episulfide optical material 可奥熙搜路司有限公司 2022-04-19 CN disclosed
CN-112118955-A Automatic injection method of mold for monomer for episulfide optical material 可奥熙搜路司有限公司 2020-12-22 CN disclosed
EP-2497791-B1 METHOD FOR PRODUCING INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION INCLUDING THE SAME MITSUI CHEMICALS INC (JP) 2020-05-13 EP disclosed
US-20200071467-A1 Polyrotaxane, Production Method Therefor, and Optical Composition Containing said Polyrotaxane TOKUYAMA CORPORATION (JP) 2020-03-05 US disclosed
EP-3150647-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL AND METHOD FOR PRODUCING OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2019-10-16 EP disclosed
US-RE47556-E1 Optical element compound, optical material, and optical element CANON KABUSHIKI KAISHA (JP) 2019-08-06 US disclosed
EP-2390684-B1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KK (JP) 2019-04-24 EP disclosed
EP-1058133-B1 Polymerizable composition and process for producing optical resin comprising the same MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6369269-B2 Thiol and sulfur-containing O-(meth)acrylate compounds and use thereof MITSUI CHEMICALS, INC. (JP) 2002-04-09 US disclosed
US-6365707-B1 CATALYTIC POLYEPOXIDES OR POLYTHIOEPOXIDES AND AMINO COMPOUNDS MITSUI CHEMICALS, INC. (JP) 2002-04-02 US disclosed
US-20010044555-A1 Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof KOBAYASHI SEIICHI (JP) 2001-11-22 US disclosed
US-6265510-B1 OPTICS; LENSES MITSUI CHEMICALS, INC. (JP) 2001-07-24 US disclosed
EP-0810210-B1 Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof MITSUI CHEMICALS INC (JP) 2001-01-10 EP disclosed
EP-1058133-A2 Polymerizable composition and process for producing optical resin comprising the same Mitsui Chemicals, Inc. (JP) 2000-12-06 EP disclosed
US-6114485-A STARTING MATERIAL FOR A RESIN COMPOSITION USED IN OPTICAL APPLICATIONS SUCH AS A LENS MITSUI CHEMICALS, INC. (JP) 2000-09-05 US disclosed
US-5916987-A OPTICAL RESIN; LENSES MITSUI CHEMICALS, INC. (JP) 1999-06-29 US disclosed
EP-0810210-A2 Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010044555-A1 Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof MSRB3, BHMT2, HBS1L FOLH1 4227/4885DCLRE1A 821/4885DCLRE1B 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.