⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800363 | 0.84 | — | — | |
| SCHEMBL18600377 | 0.84 | — | — | |
| SCHEMBL6949290 | 0.82 | CHRNA7 (0.45) | — | |
| Tert-Butyl Formate SCHEMBL28829544 | 0.78 | TDP1 (0.43) | — | |
| SCHEMBL4043067 | 0.77 | MAOA (0.39) | — | |
| SCHEMBL8108846 | 0.74 | CHRNA7 (0.47) | — | |
| SCHEMBL6945248 | 0.74 | CHRNA7 (0.47) | — | |
| SCHEMBL15387052 | 0.72 | — | — | |
| SCHEMBL4043261 | 0.72 | — | — | |
| SCHEMBL1955321 | 0.72 | CHRNA7 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957163-B | Preparation method of N-methyl homopiperazine | 合肥亿帆生物制药有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-114957163-A | Preparation method of N-methyl homopiperazine | 合肥亿帆生物制药有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114957163-B | Preparation method of N-methyl homopiperazine | 合肥亿帆生物制药有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-114957163-A | Preparation method of N-methyl homopiperazine | 合肥亿帆生物制药有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113620950-A | Carboxamide derivatives useful as RSK inhibitors | 凤凰分子设计公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-109071542-B | Carboxamide derivatives useful as RSK inhibitors | 凤凰分子设计公司 | 2021-07-20 | — | — | CN | disclosed |
| EP-3848373-A1 | N-(1-((HETEROCYCLYL)METHYL)-1H-PYRAZOL-4-YL)-6-OXO-6,7,8,9- TETRAHYDROPYRIDO[3',2':4,5]PYRROLO[L,2-A]PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS P90 RIBOSOMAL S6 KINASE (RSK) INHIBITORS FOR TREATING CANCER | Phoenix Molecular Designs (CA) | 2021-07-14 | — | — | EP | disclosed |
| US-20210186961-A1 | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | PHOENIX MOLECULAR DESIGNS (CA) | 2021-06-24 | — | — | US | disclosed |
| US-20210179556-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | ABBVIE INC. | 2021-06-17 | — | — | US | disclosed |
| EP-3416964-B1 | 6-OXO-N-(1-(BENZYL)-1H-PYRAZOL-4-YL)-6,7,8,9- TETRAHYDROPYRIDO[3',2':4,5]PYRROLO[1,2-A]PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS P90 RIBOSOMAL S6 KINASE (RSK) INHIBITORS FOR TREATING CANCER | PHOENIX MOLECULAR DESIGNS (CA) | 2020-12-16 | — | — | EP | disclosed |
| US-10758530-B2 | Carboxamide derivatives useful as rsk inhibitors | PHOENIX MOLECULAR DESIGNS (CA) | 2020-09-01 | — | — | US | disclosed |
| WO-2003066592-A1 | GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2003-08-14 | — | — | WO | disclosed |
| US-RE37839-E1 | O-benzyloxime ethers and crop protection agents containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |
| US-6326399-B1 | CONTROLLING INSECTS, ARACHNIDS, NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-04 | — | — | US | disclosed |
| US-6316459-B1 | O-benzyloxime ethers and crop protection agents containing these compounds | BASF AG (DE) | 2001-11-13 | — | — | US | disclosed |
| US-5563168-A | FUNGICIDES, INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5387607-A | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5292759-A | O-benzyloxime ethers and crop protection agents containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5194662-A | Insecticides, fungicides for plants | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0463488-A1 | O-Benzyl oxime ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1992-01-02 | — | — | EP | disclosed |