Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142573 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11148141 | 0.89 | PTGS1 (0.61) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11802087 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL10811020 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11055755 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11045122 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11154449 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11148136 | 0.89 | PTGS1 (0.61) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11231581 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 | |
| SCHEMBL11154468 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405778-A | Process for preparing cephalosporin ethers | CIBA-GEIGY CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |