Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | STS | P08842 | 8/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.64 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070255 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL22070254 | 0.96 | CYP3A4 (0.71) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL8903503 | 0.94 | KDM4E (0.74) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL12186933 | 0.94 | KDM4E (0.74) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL11228735 | 0.91 | KDM4E (0.60) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL3322364 | 0.90 | CYP3A4 (0.66) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL26659900 | 0.90 | CYP3A4 (0.66) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL7992527 | 0.88 | CYP3A4 (0.72) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL10710176 | 0.87 | CYP3A4 (0.73) | KDM4EALDH1A1CYP3A4HSD17B1MAPT | |
| SCHEMBL19393194 | 0.87 | STS (0.68) | KDM4EALDH1A1CYP3A4HSD17B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376825-A | ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS | SYVA COMPANY (US) | 1983-03-15 | — | — | US | disclosed |
| EP-0062632-A1 | STERIC HINDRANCE ENZYME IMMUNOASSAY | UNIVERSITY OF MIAMI (US) | 1982-10-20 | — | — | EP | disclosed |
| WO-1982001378-A1 | STERIC HINDRANCE ENZYME IMMUNOASSAY | UNIV MIAMI (US) | 1982-04-29 | — | — | WO | disclosed |
| US-4282325-A | FOR AMPLIFICATION IN ASSAYS | SYVA COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4203802-A | ENZYME BOUND TO AN ESTROGEN LIGAND | SYVA COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4190496-A | RECEPTOR, LIGAND, AND ENZYME-BOUND | SYVA COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4067774-A | Compounds for enzyme amplification assay | SYVA COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3975237-A | LIGANDS | SYVA COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3966764-A | ELECTRON SPIN RESONANCE | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966556-A | Compounds for enzyme amplification assay methadone analogs | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966744-A | Spin labeled compounds | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |