Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143369 | 0.95 | BACE1 (0.39) | BACE1SCN9APTGS1CTSSCTSK | |
| SCHEMBL11143825 | 0.92 | SCN9A (0.37) | BACE1SCN9APTGS1CTSSCTSK | |
| SCHEMBL11464559 | 0.85 | PTGS1 (0.50) | MAPTSLC22A6SLC22A8PDE3ASLC22A11 | |
| SCHEMBL11670093 | 0.84 | PTGS1 (0.48) | MAPTSLC22A6SLC22A8SLC22A11SCN9A | |
| SCHEMBL11670596 | 0.84 | PTGS1 (0.48) | MAPTSLC22A6SLC22A8SLC22A11SCN9A | |
| SCHEMBL11149699 | 0.78 | PTGS1 (0.46) | MAPTSLC22A6SLC22A8PDE3ASLC22A11 | |
| SCHEMBL10706148 | 0.78 | CTDSP1 (0.43) | SCN9APTGS1CTSSCTSKTDP1 | |
| SCHEMBL11144577 | 0.77 | TDP1 (0.50) | MAPTSLC22A6SLC22A8SLC22A11PTGS1 | |
| SCHEMBL11143390 | 0.77 | NR1I2 (0.31) | MAPTSLC22A6SLC22A8SLC22A11ESR1 | |
| SCHEMBL11144584 | 0.77 | TDP1 (0.50) | MAPTSLC22A6SLC22A8SLC22A11PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399278-A | 7-AMINO-2 OR 3-CEPHEM-4-CARBOXY COMPOUNDS HAVING ANTIBACTERIAL PROPERTIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |
| US-4327093-A | TREATING INFECTIONS DISEASES, ANTIBACTERIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0010313-A1 | 3,7-Disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |