Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670093 | 1.00 | PTGS1 (0.48) | PTGS1L3MBTL1CTDSP1TDP1CTSS | |
| SCHEMBL10706148 | 0.93 | CTDSP1 (0.43) | PTGS1L3MBTL1CTDSP1TDP1CTSS | |
| SCHEMBL11143369 | 0.89 | BACE1 (0.39) | PTGS1L3MBTL1CTDSP1TDP1CTSS | |
| SCHEMBL11707096 | 0.85 | CTSS (0.43) | CTDSP1CTSSCTSKSCN9AELANE | |
| SCHEMBL11143849 | 0.84 | MAPT (0.35) | PTGS1TDP1CTSSCTSKSCN9A | |
| SCHEMBL10811905 | 0.83 | PTGS1 (0.71) | PTGS1L3MBTL1CTDSP1TDP1MAPT | |
| SCHEMBL11215786 | 0.83 | PTGS1 (0.71) | PTGS1L3MBTL1CTDSP1TDP1MAPT | |
| SCHEMBL11444166 | 0.83 | PTGS1 (0.71) | PTGS1L3MBTL1CTDSP1TDP1MAPT | |
| SCHEMBL11841581 | 0.83 | PTGS1 (0.71) | PTGS1L3MBTL1CTDSP1TDP1MAPT | |
| SCHEMBL10811911 | 0.83 | PTGS1 (0.71) | PTGS1L3MBTL1CTDSP1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013650-A | PROCESS FOR THE MANUFACTURE OF 3-METHYLENE-CEPHAM COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | claimed |
| US-4013650-A | PROCESS FOR THE MANUFACTURE OF 3-METHYLENE-CEPHAM COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |