Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | NPY4R | P50391 | 6/20 | 0.55 |
| ▸ | NPY1R | P25929 | 4/20 | 0.55 |
| ▸ | NPY2R | P49146 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11141349 | 0.99 | PSMB1 (0.57) | PSMB1PSMB5PSMB2CTSLCTSB | |
| Hydrochloric Acid SCHEMBL11141841 | 0.96 | PSMB1 (0.61) | PSMB1PSMB5PSMB2CTSLCTSB | |
| Hydrochloric Acid SCHEMBL11145577 | 0.95 | PSMB1 (0.61) | PSMB1PSMB5PSMB2CTSLCTSB | |
| SCHEMBL29742237 | 0.93 | PSMB1 (0.58) | PSMB1PSMB5PSMB2CTSLCTSB | |
| SCHEMBL10787739 | 0.90 | NPY4R (0.61) | CTSLCTSBCAPN1NPY4RNPY1R | |
| SCHEMBL10787733 | 0.90 | NPY4R (0.61) | CTSLCTSBCAPN1NPY4RNPY1R | |
| SCHEMBL6035561 | 0.89 | CAPN1 (0.63) | CTSLCTSBCAPN1NPY4RNPY1R | |
| SCHEMBL6033726 | 0.89 | CAPN1 (0.63) | CTSLCTSBCAPN1NPY4RNPY1R | |
| SCHEMBL10784684 | 0.86 | CAPN1 (0.61) | PSMB1CTSLCTSBCAPN1NPY4R | |
| SCHEMBL10784713 | 0.86 | CAPN1 (0.61) | PSMB1CTSLCTSBCAPN1NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401594-A | PROTEOLYTIC ENZYME INHIBIJTORS; CARDIOVASCULAR AND MUSCULAR DISORDERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-08-30 | — | — | US | claimed |