Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155449 | 0.89 | MAPT (0.54) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11150690 | 0.89 | MAPT (0.55) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11145457 | 0.85 | MAPT (0.51) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11146960 | 0.85 | KMT2A (0.58) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11193309 | 0.85 | PLK1 (0.60) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11146320 | 0.85 | MAPT (0.58) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL53437 | 0.84 | MAPT (0.60) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL9621048 | 0.83 | KMT2A (0.63) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL9621349 | 0.83 | MAPT (0.59) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11149337 | 0.82 | MAPT (0.53) | KMT2AMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385927-A | ETHER OF N-2,3-DICHLOROPHENYL P-HYDROXYBENZAMIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-05-31 | — | — | US | disclosed |