SCHEMBL53437

SCHEMBL53437

CCOCOc1ccc(C(=O)Nc2cccc(Cl)c2Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.60
▸ LMNA P02545 3/20 0.60
▸ POLB P06746 3/20 0.60
▸ KMT2A Q03164 7/20 0.56
▸ RAB9A P51151 5/20 0.56
▸ NPC1 O15118 4/20 0.56
▸ MEN1 O00255 4/20 0.56
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ HPGD P15428 1/20 0.56
▸ GAA P10253 2/20 0.56
▸ TP53 P04637 1/20 0.47
▸ CYP1A2 P05177 2/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11151339 0.90 MAPT (0.55) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11147514 0.90 MAPT (0.57) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11146334 0.89 MAPT (0.54) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11146960 0.89 KMT2A (0.58) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11193309 0.86 PLK1 (0.60) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL9621662 0.84 MAPT (0.83) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11149361 0.84 MAPT (0.54) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11146320 0.84 MAPT (0.58) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11144524 0.84 KMT2A (0.58) MAPTLMNAPOLBKMT2ARAB9A
SCHEMBL11146339 0.83 PLK1 (0.55) MAPTLMNAPOLBKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13117 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES FMC CORP (US) 2026-04-09 — — US claimed
EP-4714942-A1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC Corporation (US) 2026-03-25 — — EP claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 — — US claimed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 — — EP claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 — — US claimed
EP-4188093-B9 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-12-03 — — EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 — — EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 — — EP claimed
US-20250318528-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 — — US claimed
EP-4178357-B1 METHOD FOR CONTROLLING UNDESIRABLE VEGETATION IN AN AQUATIC ENVIRONMENT BASF AGRO BV (NL) 2025-09-24 — — EP claimed
EP-0861026-A1 SYNERGISTIC HERBICIDAL MIXTURES CONTAINING CYCLOHEXENONE OXIME ETHER BASF AKTIENGESELLSCHAFT (DE) 1998-09-02 — — EP claimed
EP-0859548-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1998-08-26 — — EP claimed
CN-1166274-A Herbicides based on heteroaryloxy-acetamides for use in rice cultivation BAYER AG (DE) 1997-12-03 — — CN claimed
WO-1997031535-A1 HERBICIDAL AGENTS BASED ON N-PHOSPHONOMETHYLGLYCINE ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1997-09-04 — — WO claimed
WO-1997010710-A1 SYNERGISTIC HERBICIDAL MIXTURES CONTAINING CYCLOHEXENONE OXIME ETHER BASF AKTIENGESELLSCHAFT (DE) 1997-03-27 — — WO claimed
WO-1997010714-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1997-03-27 — — WO claimed
CN-1129517-A Herbicides based on aryluracils for use in rice cultivation BAYER AG (DE) 1996-08-28 — — CN claimed
US-5420098-A Herbicidal composition comprising HW-52 and one of atrazine, cyanazine, ioxynil, bromoxynil, or metribuzin HODOGAYA CHEMICAL CO., LTD. (JP) 1995-05-30 — — US claimed
EP-0617889-A2 Herbicidal composition HODOGAYA CHEMICAL CO., LTD. (JP) 1994-10-05 — — EP claimed
EP-0456198-A1 Oil suspension concentrate for direct paddy water application HODOGAYA CHEMICAL CO., LTD. (JP) 1991-11-13 — — EP claimed
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