⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21248092 | 0.97 | IRAK4 (0.36) | — | |
| SCHEMBL19020836 | 0.89 | KDM4E (0.39) | — | |
| SCHEMBL12827029 | 0.89 | KDM4E (0.34) | — | |
| SCHEMBL11142038 | 0.88 | ALDH1A1 (0.33) | — | |
| SCHEMBL19020955 | 0.88 | IRAK4 (0.33) | — | |
| SCHEMBL23731315 | 0.88 | IRAK4 (0.33) | — | |
| SCHEMBL14644690 | 0.88 | ALDH1A1 (0.33) | — | |
| SCHEMBL19020954 | 0.88 | IRAK4 (0.33) | — | |
| SCHEMBL1356297 | 0.87 | KDM4E (0.43) | — | |
| Hydrochloric Acid SCHEMBL18987760 | 0.86 | IRAK4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | AMGEN INC. (US) | 2020-10-01 | — | — | US | disclosed |
| CN-109311887-A | Pyrazolo [1,5-a] pyrimidine radicals benzamide compound and they treatment medical conditions in purposes | 溶酶体治疗股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| WO-2019016385-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2019-01-24 | — | — | WO | disclosed |
| WO-2015185485-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2015-12-10 | — | — | WO | disclosed |
| CN-1894217-B | Substituted dibenzo-azepine and benzo-diazepine derivatives useful as gamma-secretase inhibitors | HOFFMANN LA ROCHE | 2011-09-21 | — | — | CN | disclosed |
| CN-100593539-C | Malonamide derivatives blocking the activtiy of gamma-secretase | HOFFMANN LA ROCHE | 2010-03-10 | — | — | CN | disclosed |
| CN-1894217-A | Substituted dibenzo-azepine and benzo-diazepine derivatives useful as gamma-secretase inhibitors | HOFFMANN LA ROCHE (CH) | 2007-01-10 | — | — | CN | disclosed |
| CN-1875005-A | Malonamide derivatives blocking the activtiy of gamma-secretase | HOFFMANN LA ROCHE (CH) | 2006-12-06 | — | — | CN | disclosed |
| US-4378366-A | HYPOTENSIVE AND CARDIOTONIC AGENTS; ADRENERGIC STIMULANTS | SCIENCE UNION ET CIE (FR) | 1983-03-29 | — | — | US | disclosed |