Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086668 | 0.75 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1CYP2D6 | |
| SCHEMBL17086663 | 0.75 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1CYP2D6 | |
| SCHEMBL23514871 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL17086664 | 0.72 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL19494132 | 0.72 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL17086651 | 0.72 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL17086666 | 0.72 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL17086655 | 0.72 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL5866507 | 0.71 | OPRM1 (0.42) | OPRM1OPRL1OPRD1OPRK1CYP2D6 | |
| SCHEMBL9717862 | 0.71 | OPRM1 (0.46) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4386127-A | SYNTHETIC LEATHER; SUEDE | TORAY INDUSTRIES, INC. (JP) | 1983-05-31 | — | — | US | disclosed |