SCHEMBL11145489

SCHEMBL11145489

COc1ccc([Te]c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.60
APP P05067 4/20 0.55
MAPT P10636 5/20 0.51
ALDH1A1 P00352 4/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
HSD17B10 Q99714 2/20 0.51
TP53 P04637 1/20 0.51
ESR2 Q92731 1/20 0.51
NOX1 Q9Y5S8 1/20 0.51
KDM4E B2RXH2 1/20 0.51
HPGD P15428 1/20 0.51
GAA P10253 2/20 0.47
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 3/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55926 0.87 SLC2A1 (0.75) SLC2A1APPMAPTALDH1A1NPC1
Hydrochloric Acid SCHEMBL2872287 0.84 SLC2A1 (0.72) SLC2A1APPMAPTALDH1A1NPC1
SCHEMBL6677884 0.84 CA1 (0.65) MAPTALDH1A1NPC1RAB9AESR2
Bromide SCHEMBL11229102 0.82 CA1 (0.61) MAPTALDH1A1NPC1RAB9AESR2
Hydrochloric Acid SCHEMBL11578310 0.82 ALDH1A1 (0.61) SLC2A1APPMAPTALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL11146324 0.82 CA1 (0.61) MAPTALDH1A1NPC1RAB9AESR2
Hydrochloric Acid SCHEMBL11146327 0.82 CA1 (0.61) MAPTALDH1A1NPC1RAB9AESR2
Bromide SCHEMBL11574120 0.82 CA1 (0.61) MAPTALDH1A1NPC1RAB9AESR2
Iodide SCHEMBL11574058 0.82 CA1 (0.61) MAPTALDH1A1NPC1RAB9AESR2
SCHEMBL10023997 0.80 SLC2A1 (0.67) SLC2A1APPMAPTALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4370497-A Oxidation process using tellurium oxide catalysts BARTON DEREK H R (FR) 1983-01-25 US disclosed