SCHEMBL11145494

SCHEMBL11145494

B.C=Cc1ccncc1.[HH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11007081 0.97
Fluoride SCHEMBL17966114 0.94 ALDH1A1 (0.53)
SCHEMBL14867 0.94
SCHEMBL28222778 0.94 ALDH1A1 (0.59)
Charcoal, Activated SCHEMBL6425744 0.92
Bromide SCHEMBL3107187 0.92 ALDH1A1 (0.56)
SCHEMBL1462870 0.92
SCHEMBL8609621 0.92
Hydrochloric Acid SCHEMBL220696 0.92
SCHEMBL9405395 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4410665-A ((DIMETHYLAMINO)PROPYL)METHACRYLAMIDE-PHOSPHINE BORANE ADDUCT COPOLYMER, REDUCING AGENTS ROHM AND HAAS COMPANY (US) 1983-10-18 US disclosed
US-4355140-A CROSSLINKED RESIN WITH AMINE OR PHOSPHINE GROUP ROHM AND HAAS COMPANY (US) 1982-10-19 US disclosed
US-4311812-A Borane reducing resins ROHM AND HAAS COMPANY (US) 1982-01-19 US disclosed
US-4311811-A Borane reducing resins ROHM AND HAAS COMPANY (US) 1982-01-19 US disclosed
US-4240909-A NONIONIC AMINE-BORANE OR PHOSPHINE-BORANE ADDUCTS ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4223173-A NONIONIC CROSSLINKED RESIN CONTAINING AMINE OR PHOSPHINE GROUPS ADDUCTED TO BORANE; HYDROGENATING OLEFINS, KETONES OR ALDEHYDES ROHM AND HAAS COMPANY (US) 1980-09-16 US disclosed