SCHEMBL11145508

SCHEMBL11145508

CC=CC(=O)C1(C)CC=C(C)CC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GLI1 P08151 1/20 0.30
CYP3A4 P08684 1/20 0.30
GLI2 P10070 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148273 1.00 GLI1 (0.30) GLI1CYP3A4GLI2
SCHEMBL20446702 0.77 GLI1 (0.34) GLI1CYP3A4GLI2
SCHEMBL3505753 0.77 GLI1 (0.34) GLI1CYP3A4GLI2
SCHEMBL1751400 0.77 FFAR3 (0.44) GLI1CYP3A4GLI2
SCHEMBL18466440 0.77 FFAR3 (0.44) GLI1CYP3A4GLI2
SCHEMBL11147806 0.73 ALDH1A1 (0.33) CYP3A4
SCHEMBL11147810 0.73 ALDH1A1 (0.33) CYP3A4
SCHEMBL25905863 0.72 SMN1; SMN2 (0.35) GLI1CYP3A4GLI2
SCHEMBL29827658 0.72 SMN1; SMN2 (0.35) GLI1CYP3A4GLI2
SCHEMBL13105307 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4392993-A DIMETHYLCYCLOHEXENYL PROPENYL KETONES; UPGRADING ODORS FIRMENICH, SA (CH) 1983-07-12 US claimed
US-4392993-A DIMETHYLCYCLOHEXENYL PROPENYL KETONES; UPGRADING ODORS FIRMENICH, SA (CH) 1983-07-12 US disclosed