Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154663 | 0.88 | POLB (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL26262293 | 0.87 | ACACB (0.62) | NPC1RAB9AKMT2AMEN1EPHX2 | |
| SCHEMBL3845087 | 0.83 | ALDH1A1 (0.68) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5241790 | 0.81 | NPC1 (0.61) | NPC1RAB9AKMT2AMEN1EPHX2 | |
| SCHEMBL15514715 | 0.81 | NPC1 (0.66) | NPC1RAB9AKMT2AMEN1EPHX2 | |
| SCHEMBL11151798 | 0.80 | ALDH1A1 (0.50) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11147145 | 0.79 | NPC1 (0.59) | NPC1RAB9ANR1H4SMN1; SMN2ALDH1A1 | |
| SCHEMBL28396081 | 0.79 | MAPK14 (0.59) | NPC1RAB9AKMT2AMEN1EPHX2 | |
| SCHEMBL11731507 | 0.78 | KMT2A (0.65) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13192880 | 0.77 | RNF4 (0.62) | NPC1KMT2AMEN1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4398944-A | N-ALKOXYPHENYLMETHYL-2-CHLOROACETAMIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-08-16 | — | — | US | claimed |