SCHEMBL11146499

SCHEMBL11146499

CCOC(=O)/C(=C\C(=O)OC)CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.48
GLO1 Q04760 1/20 0.39
ALDH1A1 P00352 5/20 0.39
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
SOAT1 P35610 1/20 0.38
EGLN1 Q9GZT9 1/20 0.37
CYP2C9 P11712 1/20 0.37
HCAR2 Q8TDS4 2/20 0.36
MAPT P10636 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148529 1.00 NPSR1 (0.48) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11143335 0.88 NPSR1 (0.63) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL7770887 0.88 NPSR1 (0.63) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11143394 0.88 NPSR1 (0.63) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
Ammonia Solution, Strong SCHEMBL5954218 0.86 NPSR1 (0.61) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL7774759 0.85 HCAR2 (0.40) NPSR1ALDH1A1EGLN1HCAR2KEAP1
SCHEMBL10430503 0.85 HCAR2 (0.40) NPSR1ALDH1A1EGLN1HCAR2KEAP1
SCHEMBL9304844 0.85 HCAR2 (0.40) NPSR1ALDH1A1EGLN1HCAR2KEAP1
SCHEMBL11146493 0.84 NPSR1 (0.53) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11148527 0.84 NPSR1 (0.53) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4383053-A Antifouling paints having fumaric acid ester polymer NIPPON OIL AND FATS CO., LTD. (JP) 1983-05-10 US disclosed