Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114788 | 1.00 | CCR2 (0.52) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL5699632 | 1.00 | CCR2 (0.52) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL5699622 | 1.00 | CCR2 (0.52) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114631 | 0.95 | CCR2 (0.47) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114932 | 0.80 | CCR2 (0.60) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114962 | 0.80 | CCR2 (0.60) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114852 | 0.80 | CCR2 (0.60) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114672 | 0.80 | CCR2 (0.60) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114444 | 0.80 | CCR2 (0.60) | CCR2GNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1114510 | 0.80 | CCR2 (0.60) | CCR2GNAI3GNAO1GNAI1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279741-A2 | Caprolactams and their use as anti-inflammatory agents | Cambridge Enterprise Ltd. (GB) | 2011-02-02 | — | — | EP | claimed |
| EP-1691814-A2 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2006-08-23 | — | — | EP | claimed |
| WO-2005053702-A2 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2005-06-16 | — | — | WO | claimed |
| EP-1691814-A2 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005053702-A2 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2005-06-16 | — | — | WO | disclosed |