Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 19/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146707 | 1.00 | PI4KB (0.65) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11146705 | 1.00 | PI4KB (0.65) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL29367493 | 0.88 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL146323 | 0.88 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL10429408 | 0.88 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL10429409 | 0.88 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145549 | 0.86 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11150109 | 0.86 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11147977 | 0.86 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145535 | 0.86 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420479-A | 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES | ELI LILLY AND COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| EP-0091794-A1 | Process for preparing 1.6-disubstituted 2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |