Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319822 | 0.84 | MAPT (0.45) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL27847176 | 0.78 | CYP1A2 (0.44) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL21359793 | 0.78 | CYP1A2 (0.44) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL22726955 | 0.77 | MAPT (0.40) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL12345499 | 0.77 | ALDH1A1 (0.40) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| Ethylene SCHEMBL29270268 | 0.74 | CYP1A2 (0.44) | GAATLR8MCHR1 | |
| SCHEMBL740412 | 0.73 | CYP1A2 (0.47) | GAATLR8MCHR1 | |
| SCHEMBL14897790 | 0.72 | ALDH1A1 (0.36) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10759911 | 0.72 | MAPT (0.37) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL14254801 | 0.72 | PTGS1 (0.38) | MAPTKDM4EMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4381308-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-04-26 | — | — | US | disclosed |