Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 19/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149101 | 0.90 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11160244 | 0.88 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL4837467 | 0.87 | PI4KB (0.74) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL10906292 | 0.87 | PI4KB (0.74) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11157833 | 0.87 | PI4KB (0.67) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11148734 | 0.87 | PI4KB (0.67) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11150664 | 0.86 | PI4KB (0.66) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11073939 | 0.84 | PI4KB (0.72) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145881 | 0.83 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11145546 | 0.83 | PI4KB (0.69) | PI4KBMAPK14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420479-A | 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES | ELI LILLY AND COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| EP-0091795-A1 | Olefinic benzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |
| EP-0091794-A1 | Process for preparing 1.6-disubstituted 2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |