Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 14/20 | 0.50 |
| ▸ | MEN1 | O00255 | 14/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.50 |
| ▸ | MAPT | P10636 | 12/20 | 0.50 |
| ▸ | BLM | P54132 | 9/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.50 |
| ▸ | RECQL | P46063 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149660 | 0.76 | EP300 (0.43) | MEN1KMT2AMAPTL3MBTL1RECQL | |
| SCHEMBL4604008 | 0.75 | MAPT (0.57) | POLBMEN1KMT2AMAPTBLM | |
| SCHEMBL11149254 | 0.74 | MEN1 (0.73) | POLBMEN1KMT2AMAPTBLM | |
| SCHEMBL11153582 | 0.72 | MAPT (0.49) | POLBMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11145679 | 0.70 | MAPK1 (0.43) | MEN1KMT2AMAPTL3MBTL1RECQL | |
| SCHEMBL20718846 | 0.70 | TDP1 (0.54) | POLBMEN1KMT2AMAPTBLM | |
| SCHEMBL22095990 | 0.69 | ITGA4 (0.70) | POLBMEN1KMT2AMAPTBLM | |
| SCHEMBL20718844 | 0.69 | MEN1 (0.59) | POLBMEN1KMT2AMAPTBLM | |
| SCHEMBL29489704 | 0.68 | ITGA4 (0.61) | POLBMEN1KMT2AMAPTBLM | |
| SCHEMBL20726639 | 0.67 | MEN1 (0.54) | POLBMEN1KMT2AMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |