Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528806 | 0.81 | NPC1 (0.55) | NPSR1ALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL30143994 | 0.79 | NPSR1 (0.45) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL13943352 | 0.79 | NPSR1 (0.45) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL1418065 | 0.78 | PDE10A (0.39) | NPSR1ALDH1A1L3MBTL1KDM4ENPC1 | |
| SCHEMBL630362 | 0.78 | NPSR1 (0.43) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL7456714 | 0.78 | ALDH1A1 (0.50) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL29574660 | 0.78 | NPSR1 (0.43) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL11527908 | 0.78 | NPSR1 (0.43) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL27957867 | 0.76 | NPSR1 (0.42) | NPSR1CSNK2A1ALDH1A1MAPK1ATM | |
| SCHEMBL6645577 | 0.76 | CDC25B (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279178-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2011-02-02 | — | — | EP | disclosed |