Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115011 | 0.90 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL1115113 | 0.89 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL1115168 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1F10 | |
| SCHEMBL1115160 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1HPGDRAB9AKMT2A | |
| SCHEMBL1115025 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL5204036 | 0.85 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL1115171 | 0.84 | PDPK1 (0.43) | PTGS2PTGS1F10 | |
| SCHEMBL1114981 | 0.84 | PTGS2 (0.46) | PTGS2PTGS1CA2CA4CA7 | |
| SCHEMBL1114947 | 0.84 | PTGS2 (0.46) | PTGS2PTGS1SMN1; SMN2RAB9A | |
| SCHEMBL1115045 | 0.82 | PTGS2 (0.41) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | claimed |
| EP-1567508-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2008-12-10 | — | — | EP | claimed |
| EP-1567508-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-31 | — | — | EP | claimed |
| US-6849652-B1 | 1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2005-02-01 | — | — | US | claimed |
| WO-2004046121-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-03 | — | — | WO | claimed |
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1567508-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2008-12-10 | — | — | EP | disclosed |
| EP-1567508-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-31 | — | — | EP | disclosed |
| US-6849652-B1 | 1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2005-02-01 | — | — | US | disclosed |
| WO-2004046121-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-03 | — | — | WO | disclosed |