Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.76 |
| ▸ | CNR2 | P34972 | 1/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131942 | 0.92 | PTGS2 (0.73) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL31097203 | 0.91 | PTGS2 (0.80) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL11148958 | 0.91 | PTGS2 (0.76) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL4370836 | 0.91 | PTGS2 (0.77) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL11150215 | 0.90 | PTGS2 (0.71) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL11208920 | 0.90 | PTGS2 (0.73) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL29355098 | 0.89 | PTGS2 (0.82) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL4549122 | 0.86 | PTGS2 (1.00) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL12988768 | 0.86 | PTGS2 (0.86) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL29855593 | 0.86 | PTGS2 (0.86) | PTGS2CNR2AKR1C3HTR1APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080271-A1 | Indomethacin phenyl ester derivatives, their use, and compositions containing them | TEIKOKU KAGAKU SANGYO K.K. (JP) | 1983-06-01 | — | — | EP | disclosed |