Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.84 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152031 | 0.83 | ALDH1A1 (0.82) | ALDH1A1GAAPOLBNPSR1ADORA2B | |
| SCHEMBL11151949 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBNPSR1ADORA2B | |
| SCHEMBL13863953 | 0.78 | ALDH1A1 (0.73) | ALDH1A1GAAPOLBNPSR1ADORA2B | |
| SCHEMBL11266479 | 0.74 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBNPSR1ADORA2B | |
| SCHEMBL24439270 | 0.74 | ALDH1A1 (0.51) | ALDH1A1GAAPOLBNPSR1KDM4E | |
| SCHEMBL1729796 | 0.71 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBNPSR1ADORA2B | |
| SCHEMBL29674700 | 0.71 | NPC1 (0.49) | ALDH1A1GAAPOLBNPSR1MAPT | |
| SCHEMBL13863955 | 0.70 | KDM4E (0.61) | ALDH1A1GAAPOLBNPSR1ADORA2B | |
| SCHEMBL24439007 | 0.70 | ALDH1A1 (0.42) | ALDH1A1GAAPOLBNPSR1 | |
| SCHEMBL13863951 | 0.70 | KDM4E (0.61) | ALDH1A1GAAPOLBNPSR1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010440-B1 | PYROMELLITIC DIIMIDES, PROCESSES FOR THEIR PREPARATION, THESE COMPOUNDS IN ORALLY ADMINISTRABLE FORM FOR USE IN INCREASING THE FEED EFFICIENCY OF A RUMINANT ANIMAL AND COMPOSITIONS FOR THIS PURPOSE CONTAINING THEM | MERCK & CO. INC. (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4289784-A | ASYMMETRICALLY SUBSTITUTED | MERCK & CO., INC. (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0010440-A1 | Pyromellitic diimides, processes for their preparation, these compounds in orally administrable form for use in increasing the feed efficiency of a ruminant animal and compositions for this purpose containing them | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |