SCHEMBL11150613

SCHEMBL11150613

CCN(CC)NC1C2CC3CC(C2)CC1C3

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
EPHX2 P34913 8/20 0.39
USP2 O75604 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11153450 0.98 L3MBTL1 (0.40) L3MBTL1EPHX2USP2CA1CA2
SCHEMBL11150896 0.80 L3MBTL1 (0.40) L3MBTL1EPHX2USP2CA1CA2
Hydrochloric Acid SCHEMBL11153647 0.78 L3MBTL1 (0.39) L3MBTL1EPHX2USP2CA1CA2
SCHEMBL11152242 0.73 EPHX2 (0.41) L3MBTL1EPHX2CA1CA2MAPK1
Hydrochloric Acid SCHEMBL11150684 0.71 EPHX2 (0.39) L3MBTL1EPHX2CA1CA2MAPK1
SCHEMBL6686034 0.69 L3MBTL1 (0.45) L3MBTL1EPHX2CA1CA2
SCHEMBL14573044 0.65 EPHX2 (0.53) L3MBTL1EPHX2
SCHEMBL11150227 0.65 L3MBTL1 (0.42) L3MBTL1EPHX2USP2CA1CA2
SCHEMBL2604739 0.64 EPHX2 (0.46) L3MBTL1EPHX2CA1CA2
SCHEMBL12408108 0.64 EPHX2 (0.46) L3MBTL1EPHX2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002066-B1 2-ADAMANTYL HYDRAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Teva Pharmaceutical Industries Limited (IL) 1983-05-25 EP claimed
EP-0002066-A1 2-Adamantyl hydrazines and pharmaceutical compositions containing them Teva Pharmaceutical Industries Limited (IL) 1979-05-30 EP claimed
EP-0002066-B1 2-ADAMANTYL HYDRAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Teva Pharmaceutical Industries Limited (IL) 1983-05-25 EP disclosed
US-4254128-A 2-Adamantyl hydrazines and biocidal compositions thereof TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1981-03-03 US disclosed
EP-0002066-A1 2-Adamantyl hydrazines and pharmaceutical compositions containing them Teva Pharmaceutical Industries Limited (IL) 1979-05-30 EP disclosed