Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650906 | 0.87 | TDP1 (0.49) | TSHRTDP1MAPTPOLBALDH1A1 | |
| SCHEMBL11150115 | 0.84 | TDP1 (0.62) | TSHRMAPK1TDP1MAPTS1PR4 | |
| SCHEMBL10854101 | 0.83 | TSHR (0.51) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL11152258 | 0.83 | TSHR (0.61) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL11155633 | 0.82 | TSHR (0.47) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL11087821 | 0.80 | TSHR (0.49) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL11781925 | 0.80 | TDP1 (0.50) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL11151249 | 0.79 | TSHR (0.47) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL11155616 | 0.78 | TSHR (0.44) | TSHRMAPK1TDP1MAPTPOLB | |
| SCHEMBL10888484 | 0.78 | GAA (0.48) | TSHRMAPK1TDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401461-A | PRE- AND POSTEMERGENCE HERBICIDES; RICE | ROHM AND HAAS COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4039588-A | ALKOXY, AMINO, HALO-, OR CYANO-SUBSTITUTED | ROHM AND HAAS COMPANY (US) | 1977-08-02 | — | — | US | disclosed |