Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154715 | 0.91 | TDP1 (0.46) | TDP1MAPK1TSHRALDH1A1HTT | |
| SCHEMBL11087821 | 0.90 | TSHR (0.49) | TDP1MAPK1TSHRALDH1A1HTT | |
| SCHEMBL11160174 | 0.85 | MAPT (0.47) | TDP1MAPK1TSHRALDH1A1LMNA | |
| Chlomethoxyfen SCHEMBL8538106 | 0.85 | TDP1 (0.68) | TDP1MAPK1TSHRALDH1A1HTT | |
| Chlomethoxyfen SCHEMBL38653 | 0.85 | TDP1 (0.68) | TDP1MAPK1TSHRALDH1A1HTT | |
| SCHEMBL7937740 | 0.84 | TDP1 (0.50) | TDP1MAPK1TSHRALDH1A1HTT | |
| SCHEMBL10854101 | 0.84 | TSHR (0.51) | TDP1MAPK1TSHRALDH1A1HTT | |
| SCHEMBL11152258 | 0.84 | TSHR (0.61) | TDP1MAPK1TSHRALDH1A1HTT | |
| SCHEMBL10817393 | 0.83 | ALDH1A1 (0.56) | TDP1MAPK1ALDH1A1HTTLMNA | |
| SCHEMBL11150111 | 0.83 | S1PR4 (0.45) | TDP1MAPK1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966453-A | Herbicidal 2-halo-4-trifluoromethyl-4'-cyanophenyl-ethers | ISHIHARA SANGYO KAISHA LTD. (JA) | 1976-06-29 | — | — | US | disclosed |