Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816670 | 0.90 | TSHR (0.41) | TSHRPPARDMAPTMAPK1ALDH1A1 | |
| SCHEMBL10876807 | 0.85 | PPARD (0.46) | TSHRPPARDMAPTMAPK1ALDH1A1 | |
| SCHEMBL12410134 | 0.82 | TSHR (0.38) | TSHRPPARDMAPTMAPK1CYP3A4 | |
| SCHEMBL816257 | 0.82 | TSHR (0.44) | TSHRPPARDMAPTMAPK1ALDH1A1 | |
| SCHEMBL7055979 | 0.82 | MAPT (0.47) | TSHRPPARDMAPTMAPK1ALDH1A1 | |
| SCHEMBL16044841 | 0.81 | TSHR (0.35) | TSHRPPARDALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL10879374 | 0.80 | ALDH1A1 (0.41) | TSHRPPARDMAPTMAPK1ALDH1A1 | |
| SCHEMBL10877831 | 0.80 | TSHR (0.43) | TSHRPPARDMAPTMAPK1CYP3A4 | |
| SCHEMBL7619464 | 0.80 | TSHR (0.43) | TSHRPPARDMAPTMAPK1CYP3A4 | |
| SCHEMBL31516116 | 0.79 | CYP2C19 (0.40) | TSHRALDH1A1CYP3A4CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091525-A2 | Phosphonoalkanoylamino acids | ANALYTICAL RESEARCH PHARMACEUTICALS PTY. LTD. (AU) | 1983-10-19 | — | — | EP | disclosed |
| EP-0070131-A1 | Phosphonoalkanoylamino acids | ANALYTICAL RESEARCH PHARMACEUTICALS PTY. LTD. (AU) | 1983-01-19 | — | — | EP | disclosed |