Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141672 | 0.82 | DRD4 (0.38) | DRD4HSD17B10MAPTSLC9A1 | |
| SCHEMBL24841998 | 0.81 | DRD4 (0.37) | DRD4GABRA5GAA | |
| SCHEMBL9933973 | 0.81 | DRD4 (0.40) | DRD4GABRA5ALDH1A1KDM4EHPGD | |
| SCHEMBL24501603 | 0.80 | DRD4 (0.38) | DRD4KDM4ETDP1MEN1KMT2A | |
| SCHEMBL24656020 | 0.80 | DRD4 (0.38) | DRD4GABRA5TDP1MEN1KMT2A | |
| SCHEMBL11166846 | 0.80 | DRD4 (0.38) | DRD4KDM4EHPGDLMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL29915606 | 0.79 | DRD4 (0.40) | DRD4TDP1ALOX15 | |
| SCHEMBL24843108 | 0.79 | DRD4 (0.36) | DRD4ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL25253616 | 0.78 | DRD4 (0.39) | DRD4ALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL25246743 | 0.78 | SLC6A2 (0.39) | DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11331391-B2 | Phosphonate-drug conjugates | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2022-05-17 | — | — | US | disclosed |
| US-20190030172-A1 | Phosphonate-Drug Conjugates | UNIVERSITY OF SOUTHERN CALIFORNIA | 2019-01-31 | — | — | US | disclosed |
| WO-2017132263-A1 | PHOSPHONATE-DRUG CONJUGATES | SEWELL, William (US) | 2017-08-03 | — | — | WO | disclosed |
| US-4396710-A | Photographic recording material with metal complexable, heterocyclic azo dye | AFGA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1983-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331391-B2 | Phosphonate-drug conjugates | MYOC, PTAFR, MTMR1 | DRD4 4853/4885GABRA5 2647/4885ALDH1A1 2272/4885 |
| US-20190030172-A1 | Phosphonate-Drug Conjugates | MYOC, PTAFR, MTMR1 | DRD4 4853/4885GABRA5 2647/4885ALDH1A1 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.