Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | RECQL | P46063 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003447 | 0.80 | MAOA (0.72) | MAOAMAPTALDH1A1TDP1HPGD | |
| SCHEMBL10402000 | 0.80 | MAOA (0.72) | MAOAMAPTALDH1A1TDP1HPGD | |
| SCHEMBL11157538 | 0.80 | MAOA (0.65) | MAOAMAPTALDH1A1TDP1HPGD | |
| SCHEMBL11062611 | 0.76 | IDO1 (0.60) | MAPTALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL23271826 | 0.74 | MAOA (0.62) | MAOAMAPTALDH1A1TDP1HPGD | |
| SCHEMBL30003503 | 0.74 | MAOA (0.62) | MAOAMAPTALDH1A1TDP1HPGD | |
| SCHEMBL5174518 | 0.74 | MAOA (0.62) | MAOAMAPTALDH1A1TDP1HPGD | |
| SCHEMBL875843 | 0.72 | MAPT (0.86) | MAOAMAPTALDH1A1TDP1HPGD | |
| Anthrarufin SCHEMBL187843 | 0.72 | MAOA (1.00) | MAOAMAPTALDH1A1TDP1HPGD | |
| Anthrarufin SCHEMBL29874705 | 0.72 | MAOA (1.00) | MAOAMAPTALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011601-B1 | DERIVATIVES OF 1H-INDEN-1-ONE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MICROBICIDAL AGENTS AND IN COMBATING MICROORGANISMS | CIBA-GEIGY AG (CH) | 1983-02-09 | — | — | EP | disclosed |