Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691062 | 0.81 | PTGDR2 (0.68) | NPC1RAB9AMAPTPTGDR2TDP1 | |
| SCHEMBL220452 | 0.80 | NPC1 (0.59) | NPC1RAB9AMAPTPTGDR2KMT2A | |
| SCHEMBL22633476 | 0.79 | TDP1 (0.58) | NPC1RAB9AMAPTTDP1LMNA | |
| SCHEMBL13446708 | 0.79 | NPC1 (0.54) | NPC1RAB9AMAPTPTGDR2CCR5 | |
| SCHEMBL11165562 | 0.79 | TDP1 (0.58) | NPC1RAB9AMAPTTDP1LMNA | |
| SCHEMBL11280539 | 0.78 | NPC1 (0.61) | NPC1RAB9AMAPTPTGDR2KMT2A | |
| SCHEMBL12781079 | 0.77 | NPC1 (0.52) | NPC1RAB9AMAPTPTGDR2CCR5 | |
| SCHEMBL1714092 | 0.75 | NPC1 (0.54) | NPC1RAB9AMAPTPTGDR2KMT2A | |
| SCHEMBL21436682 | 0.75 | NPC1 (0.53) | NPC1RAB9AMAPTPTGDR2KMT2A | |
| SCHEMBL4212506 | 0.75 | NPC1 (0.53) | NPC1RAB9AMAPTPTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414020-A | AMIDOXIMES AS SAFENING AGENTS | HOECHST AG (DE) | 1983-11-08 | — | — | US | disclosed |