Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954647 | 0.82 | ALDH1A1 (0.39) | CYP2C9CYP2C19 | |
| SCHEMBL29519413 | 0.77 | PTGS1 (0.41) | GRIA4PTGS1MEN1PTGS2KMT2A | |
| SCHEMBL11996557 | 0.75 | GRIA4 (0.43) | GRIA4PTGS1MEN1PTGS2KMT2A | |
| SCHEMBL30931034 | 0.74 | DHODH (0.40) | GRIA4PTGS1MEN1PTGS2KMT2A | |
| SCHEMBL20534566 | 0.74 | ALDH1A1 (0.51) | MEN1KMT2ALMNACYP1A2MAPT | |
| SCHEMBL11153493 | 0.73 | AKR1C3 (0.56) | PTGS1MEN1PTGS2KMT2AFABP2 | |
| SCHEMBL10795774 | 0.73 | CA12 (0.39) | PTGS2TSHRCYP1A2CYP2C9HPGD | |
| SCHEMBL7037138 | 0.72 | AKR1C3 (0.59) | PTGS1MEN1PTGS2KMT2AFABP2 | |
| SCHEMBL13776977 | 0.72 | AKR1C3 (0.59) | PTGS1MEN1PTGS2KMT2AFABP2 | |
| SCHEMBL29724711 | 0.72 | AKR1C3 (0.59) | PTGS1MEN1PTGS2KMT2AFABP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370278-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1983-01-25 | — | — | US | claimed |