Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951496 | 0.76 | GBA1 (0.36) | MAOAMAOBALDH1A1KMT2ACYP1A2 | |
| SCHEMBL11168608 | 0.75 | KMT2A (0.35) | ALDH1A1KMT2ASLC2A1GBA1 | |
| SCHEMBL6692899 | 0.75 | KMT2A (0.35) | ALDH1A1KMT2ASLC2A1GBA1 | |
| SCHEMBL10494857 | 0.73 | GBA1 (0.34) | MAOAMAOBALDH1A1KMT2AMEN1 | |
| SCHEMBL11163048 | 0.72 | — | — | |
| SCHEMBL780415 | 0.69 | SLC2A1 (0.38) | ALDH1A1KMT2AMEN1SLC2A1GBA1 | |
| SCHEMBL776553 | 0.69 | GBA1 (0.44) | ALDH1A1KMT2AMEN1MAPTSLC2A1 | |
| SCHEMBL11444364 | 0.69 | CYP1A2 (0.30) | CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14365648 | 0.67 | — | — | |
| SCHEMBL779637 | 0.66 | SLC2A1 (0.34) | KMT2ASLC2A1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370278-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1983-01-25 | — | — | US | disclosed |