SCHEMBL6692899

SCHEMBL6692899

O=[C]CSC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 3/20 0.35
SLC2A1 P11166 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GBA1 P04062 2/20 0.31
HPGD P15428 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11168608 1.00 KMT2A (0.35) KMT2AALDH1A1SLC2A1GAARAB9A
SCHEMBL11163048 0.97
SCHEMBL21253056 0.87
SCHEMBL11158282 0.75 MAOA (0.35) KMT2AALDH1A1SLC2A1GBA1
SCHEMBL780415 0.69 SLC2A1 (0.38) KMT2AALDH1A1SLC2A1GAARAB9A
SCHEMBL776553 0.69 GBA1 (0.44) KMT2AALDH1A1SLC2A1GAARAB9A
SCHEMBL8654456 0.67
SCHEMBL8698883 0.67 GBA1 (0.39) KMT2AALDH1A1SLC2A1GAARAB9A
SCHEMBL2122298 0.67 GBA1 (0.39) KMT2AALDH1A1SLC2A1GAARAB9A
SCHEMBL779637 0.66 SLC2A1 (0.34) KMT2ASLC2A1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
EP-0987567-B1 A sulfur-containing (thio)ether (co)polymer and a use thereof MITSUI CHEMICALS INC (JP) 2004-04-07 EP disclosed
US-6320020-B1 POLYMER OR COPOLYMER CONTAINING A SULFUR ATOM WHOSE PRINCIPAL BACKBONE COMPRISES ETHER AND/OR THIOETHER BONDS; OPTICAL DISK SUBSTRATE; A LIQUID-CRYSTAL PLASTIC SUBSTRATE; VARIOUS OPTICAL LENSES INCLUDING AN EYEGLASS; AND AN LED SEALING COAT. MITSUI CHEMICALS, INC. (JP) 2001-11-20 US disclosed
EP-0987567-A1 A sulfur-containing (thio)ether (co)polymer and a use thereof Mitsui Chemicals, Inc. (JP) 2000-03-22 EP disclosed
US-4931555-A CEPHALOSPORINS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-06-05 US disclosed
US-4435321-A BACTERICIDES AND INTERMEDIATES FOR 2- OR 3-CEPHEMS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-03-06 US disclosed
US-4410458-A GROUP 5B OR 6B METAL COMPOUND OXIDATION CATALYST FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-10-18 US disclosed
US-4334014-A CONTAINING A CEPHALOSPORIN FUJI PHOTO FILM CO., LTD. (JP) 1982-06-08 US disclosed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US disclosed
US-4215043-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-07-29 US disclosed
US-4169150-A MUSCLE RELAXANTS, HYPNOSIS, ANTICONVULSANTS, SEDATIVES TEIJIN LIMITED (JP) 1979-09-25 US disclosed
US-4159984-A METAL AND PROTON DONOR SHIONOGI & CO., LTD. (JP) 1979-07-03 US disclosed
US-4138553-A 3-Methylene cephalosporanic acid derivatives and process for preparation thereof TEIJIN LIMITED (JP) 1979-02-06 US disclosed
US-4071527-A Certain benzothiazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US disclosed
US-4036847-A ANTIBACTERIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-07-19 US disclosed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US disclosed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US disclosed