Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9068199 | 0.98 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MAPK1TSHRTP53 | |
| SCHEMBL1027879 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1TSHRTP53 | |
| SCHEMBL17858561 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10MAPK1TSHRTP53 | |
| SCHEMBL14513895 | 0.75 | TDP1 (0.37) | ALDH1A1HSD17B10MAPK1TSHRTDP1 | |
| SCHEMBL2174611 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HSD17B10MAPK1TSHRTDP1 | |
| SCHEMBL2174615 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HSD17B10MAPK1TSHRTDP1 | |
| SCHEMBL80210 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1MAPTRAB9A | |
| SCHEMBL3675301 | 0.73 | ESR1 (0.44) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL14607508 | 0.72 | — | — | |
| SCHEMBL9690365 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962271-B2 | Fructosyl peptidyl oxidase | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2015-02-24 | — | — | US | claimed |
| EP-2462239-B1 | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein | ROCHE DIAGNOSTICS GMBH (DE) | 2014-09-17 | — | — | EP | claimed |
| US-20140227728-A1 | NOVEL FRUCTOSYL PEPTIDYL OXIDASE | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-08-14 | — | — | US | claimed |
| US-8721853-B2 | Fructosyl peptidyl oxidase | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-05-13 | — | — | US | claimed |
| US-20120202235-A1 | NOVEL FRUCTOSYL PEPTIDYL OXIDASE | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2012-08-09 | — | — | US | claimed |
| US-20230365944-A1 | ENGINEERED STABLE LACTATE OXIDOREDUCTASES, COMPOSITIONS, DEVICES, KITS AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2023-11-16 | — | — | US | disclosed |
| US-20220396822-A1 | Method for Measuring Pentosidine and Measurement Kit | KIKKOMAN CORPORATION (JP) | 2022-12-15 | — | — | US | disclosed |
| EP-4023754-A1 | METHOD FOR MEASURING PENTOSIDINE AND MEASUREMENT KIT | Kikkoman Corporation (JP) | 2022-07-06 | — | — | EP | disclosed |
| US-11029309-B2 | Composition comprising up-converting phosphors for detecting an analyte | ROCHE DIABETES CARE, INC. (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3074524-B1 | COMPOSITION COMPRISING UP-CONVERTING PHOSPHORS FOR DETECTING AN ANALYTE | ROCHE DIABETES CARE GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |
| US-20190113506-A1 | COMPOSITION COMPRISING UP-CONVERTING PHOSPHORS FOR DETECTING AN ANALYTE | ROCHE DIABETES CARE, INC. (US) | 2019-04-18 | — | — | US | disclosed |
| EP-2462223-B1 | FRUCTOSYL AMINO ACID OXIDASE | ROCHE DIABETES CARE GMBH (DE) | 2019-02-13 | — | — | EP | disclosed |
| US-5206147-A | COLORIMETRIC ASSAY BY ENZYMATIC OXIDATION IN THE PRESENCE OF AN AROMATIC NITROSO OR OXIME COMPOUND | BOEHRINGER MANNHEIM GMBH (DE) | 1993-04-27 | — | — | US | disclosed |
| WO-1992015879-A1 | TEST CARRIER FOR DETERMINING AN ANALYTE IN WHOLE BLOOD | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-17 | — | — | WO | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0478052-A1 | Liquid-crystalline and infrared-sensitive liquid-crystalline polyesters suitable for use in optical data storage, processes for the preparation of same, and an apparatus containing an infrared-sensitive liquid-crystalline polyester | Akzo Nobel N.V. (NL) | 1992-04-01 | — | — | EP | disclosed |
| US-5078749-A | Hair dyes, alkalizing agent for improved penetration of keratin fibers | CLAIROL, INC. (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-5000755-A | Nitroso compounds as direct dyes | CLAIROL INCORPORATED (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0354441-A2 | Method for the colorimetric determination of analyte using enzymatic oxydation | Roche Diagnostics GmbH (DE) | 1990-02-14 | — | — | EP | disclosed |