Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843267 | 0.80 | MEN1 (0.60) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL11096921 | 0.77 | MEN1 (0.59) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL11159363 | 0.77 | PDE4A (0.60) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL5579936 | 0.75 | HTT (0.69) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL26363706 | 0.75 | HTT (0.64) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL11161995 | 0.74 | MEN1 (0.53) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL3839136 | 0.74 | KDM4E (0.60) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL11403000 | 0.74 | HTT (0.59) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL4054492 | 0.73 | HTT (0.62) | MEN1KMT2AHTTKDM4ETSHR | |
| SCHEMBL11175020 | 0.73 | MEN1 (0.59) | MEN1KMT2AHTTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030835-B1 | DERIVATIVES OF 2-SUBSTITUTED-6-PHENYL-3(2H)PYRIDAZINONE, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1983-05-11 | — | — | EP | disclosed |
| EP-0030835-A1 | Derivatives of 2-substituted-6-phenyl-3(2H)pyridazinone, their production and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-06-24 | — | — | EP | disclosed |