Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105097 | 0.88 | EPHX1 (0.66) | EPHX1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL11168169 | 0.87 | EPHX1 (0.65) | EPHX1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL11166506 | 0.86 | ALDH1A1 (0.62) | EPHX1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL11171201 | 0.86 | EPHX1 (0.67) | EPHX1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL11155564 | 0.82 | EPHX1 (0.72) | EPHX1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL11167226 | 0.81 | EPHX1 (0.59) | EPHX1ALDH1A1MAPTALOX12NPSR1 | |
| SCHEMBL11162731 | 0.81 | EPHX1 (0.58) | EPHX1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL11165536 | 0.81 | EPHX1 (0.60) | EPHX1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL11156329 | 0.81 | EPHX1 (0.63) | EPHX1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL11158642 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017484-B1 | 2-IMIDAZOLINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |