SCHEMBL1115964

SCHEMBL1115964

CCCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 13/20 0.53
▸ GNPAT O15228 1/20 0.46
▸ SLC6A5 Q9Y345 2/20 0.45
▸ EPHX2 P34913 1/20 0.44
▸ C3AR1 Q16581 1/20 0.43
▸ NPY1R P25929 1/20 0.42
▸ NPY2R P49146 1/20 0.42
▸ NPY4R P50391 1/20 0.42
▸ NPY5R Q15761 1/20 0.42
▸ FNTA P49354 1/20 0.42
▸ FNTB P49356 1/20 0.42
▸ PGGT1B P53609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1115969 1.00 NOD1 (0.53) NOD1GNPATSLC6A5EPHX2C3AR1
Hydrochloric Acid SCHEMBL3423146 0.99 NOD1 (0.52) NOD1GNPATSLC6A5EPHX2C3AR1
SCHEMBL29949573 0.93 NOD1 (0.58) NOD1GNPATSLC6A5EPHX2
Trifluoroacetic Acid SCHEMBL7445678 0.92 NPY4R (0.49) NOD1GNPATSLC6A5EPHX2C3AR1
SCHEMBL7135086 0.92 NOD1 (0.64) NOD1SLC6A5EPHX2
SCHEMBL11011526 0.92 NOD1 (0.64) NOD1SLC6A5EPHX2
SCHEMBL2343614 0.91 NOD1 (0.66) NOD1SLC6A5EPHX2
SCHEMBL359523 0.91 NOD1 (0.66) NOD1SLC6A5EPHX2
SCHEMBL2344383 0.91 NOD1 (0.66) NOD1SLC6A5EPHX2
SCHEMBL11102825 0.91 NOD1 (0.66) NOD1SLC6A5EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3272764-B1 METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2024-02-07 — — EP claimed
EP-2059258-B1 ARGININE WASH IN PROTEIN PURIFICATION USING AFFINITY CHROMATOGRAPHY WYETH LLC (US) 2019-11-13 — — EP claimed
EP-3428176-A1 WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY Novartis AG (CH) 2019-01-16 — — EP claimed
EP-2714714-B1 WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2018-06-20 — — EP claimed
EP-2513134-B1 WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2017-09-06 — — EP claimed
US-9663552-B2 Purification method for proteins, in particular antibodies, utilizing a wash solution comprising arginine at high pH for the affinity chromatography step NOVARTIS AG (CH) 2017-05-30 — — US claimed
US-9462810-B2 Method for inactivating viruses with slightly acidic arginine AJINOMOTO CO., INC. (JP) 2016-10-11 — — US claimed
EP-1958626-B1 Method for inactivating viruses by addition of slightly acidic arginine AJINOMOTO KK (JP) 2014-07-23 — — EP claimed
US-8669045-B2 Method for inactivating viruses with slightly acidic arginine AJINOMOTO CO., INC. (JP) 2014-03-11 — — US claimed
CN-103596968-A Wash solution and method for affinity chromatography NOVARTIS AG 2014-02-19 — — CN claimed
WO-2009043814-A1 ANTIFREEZE COMPOSITIONS BASF SE (CH) 2009-04-09 — — WO claimed
US-20080318300-A1 Method for Inactivating Viruses With Slightly Acidic Arginine AJINOMOTO CO., INC. (JP) 2008-12-25 — — US claimed
WO-2008101202-A1 N-17-ALKYLATED PRODRUGS OF OPIOIDS PHARMACOFORE, INC. (US) 2008-08-21 — — WO claimed
EP-1958626-A1 Method for inactivating viruses by addition of slightly acidic arginine Ajinomoto Co., Inc. (JP) 2008-08-20 — — EP claimed
US-20080064860-A1 Arginine derivative wash in protein purification using affinity chromatography WYETH (US) 2008-03-13 — — US claimed
WO-2008031020-A2 ARGININE WASH IN PROTEIN PURIFICATION USING AFFINITY CHROMATOGRAPHY WYETH (US) 2008-03-13 — — WO claimed
WO-2007140272-A2 CONTROLLED RELEASE OF PHENOLIC OPIOIDS PHARMACOFORE, INC. (US) 2007-12-06 — — WO claimed
CN-1680426-A Purification method which prevents denaturation of an antibody AJINOMOTO KK (JP) 2005-10-12 — — CN claimed
EP-1568710-A2 Antibody purification method Ajinomoto Co., Inc. (JP) 2005-08-31 — — EP claimed
US-20050176109-A1 Purification method which prevents denaturation of an antibody AJINOMOTO CO., INC. (JP) 2005-08-11 — — US claimed
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