Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654196 | 0.86 | ALDH1A1 (0.64) | LMNAKMT2AKDM4EALOX12ALDH1A1 | |
| SCHEMBL1396138 | 0.86 | ALDH1A1 (0.64) | LMNAKMT2AKDM4EALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17782099 | 0.84 | ALDH1A1 (0.62) | LMNAKMT2AKDM4EALOX12ALDH1A1 | |
| SCHEMBL3719101 | 0.83 | ALDH1A1 (0.46) | LMNAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5111603 | 0.78 | ALDH1A1 (0.51) | LMNAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL18550694 | 0.78 | ALDH1A1 (0.47) | LMNAKMT2AKDM4EALOX12ALDH1A1 | |
| SCHEMBL9311129 | 0.78 | ALDH1A1 (0.58) | LMNAKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6028756 | 0.78 | MEN1 (0.55) | LMNAKMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11161401 | 0.77 | ALDH1A1 (0.53) | LMNAKMT2AKDM4EALOX12ALDH1A1 | |
| SCHEMBL11162854 | 0.77 | EPHX1 (0.64) | LMNAKMT2AKDM4EALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017484-B1 | 2-IMIDAZOLINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |