Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889701 | 0.87 | MAPK1 (0.72) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL11159073 | 0.86 | EPHX1 (0.69) | EPHX1ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL16119683 | 0.86 | EPHX1 (0.81) | EPHX1KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL5453018 | 0.85 | GAA (0.65) | KMT2AGAAMEN1ALDH1A1MAPT | |
| SCHEMBL5444538 | 0.85 | EPHX1 (0.57) | EPHX1KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL11166525 | 0.85 | SMN1; SMN2 (0.68) | EPHX1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL3056803 | 0.84 | P2RX4 (0.62) | EPHX1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL17610005 | 0.84 | EPHX1 (0.66) | EPHX1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11166422 | 0.83 | EPHX1 (0.76) | EPHX1KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL17891689 | 0.83 | ALDH1A1 (0.69) | EPHX1KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414211-A | HYPOGLYCEMIC/- | MCNEILAB, INC. (US) | 1983-11-08 | — | — | US | disclosed |