Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CD4 | P01730 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346035 | 0.66 | CTDSP1 (0.45) | POLBLMNACTDSP1NPC1KAT6A | |
| SCHEMBL7034332 | 0.66 | CTDSP1 (0.44) | POLBLMNACTDSP1KAT6AMAPT | |
| SCHEMBL6670342 | 0.66 | CA12 (0.46) | POLBLMNAMAPTKMT2AMEN1 | |
| SCHEMBL11161996 | 0.65 | NISCH (0.50) | LMNAMAPTKMT2AMEN1TSHR | |
| SCHEMBL25045972 | 0.64 | MEN1 (0.48) | POLBCTDSP1NPC1MAPTKMT2A | |
| SCHEMBL7025423 | 0.64 | CTDSP1 (0.45) | LMNACTDSP1KAT6AMAPTKMT2A | |
| SCHEMBL1606269 | 0.63 | CTDSP1 (0.59) | LMNACTDSP1NPC1MAPTKMT2A | |
| SCHEMBL755720 | 0.62 | CA12 (0.66) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3666633 | 0.62 | MYC (0.34) | POLBMAPTKMT2AMEN1RECQL | |
| SCHEMBL8217660 | 0.61 | MAPT (0.45) | LMNANPC1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414223-A | MITICIDWS | BURROUGHS WELLCOME CO. (US) | 1983-11-08 | — | — | US | disclosed |