Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217660 | 0.94 | MAPT (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8636364 | 0.89 | HTR1A (0.49) | ALDH1A1 | |
| SCHEMBL9828029 | 0.76 | MYC (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| Caldaret SCHEMBL1650574 | 0.76 | ALDH1A1 (0.52) | ALDH1A1 | |
| Caldaret SCHEMBL2853338 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 | |
| Caldaret SCHEMBL3139412 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 | |
| Caldaret SCHEMBL29711318 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 | |
| Caldaret SCHEMBL3135751 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL8959215 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL11274237 | 0.74 | MPL (0.42) | ALDH1A1MEN1KMT2AMCOLN3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882055-B1 | POLYAZAMACROCYCLOFLUOROMONOALKYLPHOSPHONIC ACIDS, AND THEIR COMPLEXES, FOR USE AS CONTRAST AGENTS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-22 | — | — | EP | disclosed |
| US-5834456-A | MAGNETIC RESONANCE IMAGING AND IN VIVO SPECTROSCOPY OF FLUORINE; SENSITIVITY, TISSUE DISTRIBUTION | THE DOW CHEMICAL COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-4702998-A | BLEACHING | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| US-4639365-A | Gadolinium chelates as NMR contrast agents | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1987-01-27 | — | — | US | disclosed |
| EP-0197437-A2 | Processing solution for light-sensitive silver halide photographic material and its processing method | KONICA CORPORATION (JP) | 1986-10-15 | — | — | EP | disclosed |