Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525636 | 0.89 | ALDH1A1 (0.48) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL1525856 | 0.89 | MAPT (0.48) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL15561464 | 0.85 | NPC1 (0.64) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL3195875 | 0.82 | HPGD (0.64) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL15561459 | 0.80 | KMT2A (0.52) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL31119121 | 0.80 | HTT (0.69) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL5707054 | 0.80 | HTT (0.69) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL31119120 | 0.80 | HTT (0.69) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL1525851 | 0.80 | MAPT (0.42) | HPGDHTTHSD17B10NAAANPC1 | |
| SCHEMBL16353997 | 0.80 | ALDH1A1 (0.42) | HPGDHTTHSD17B10NAAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096795-A2 | N-aryl pyridones, their preparation and use | BAYER AG (DE) | 1983-12-28 | — | — | EP | disclosed |